Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep383 | Endocrine-Related Cancer | ECE2021

Paraganglioma of the basis cranii due to somatic mutations ind SDHB and PTEN genes

Main Ailsa Maria , Klose Marianne , Rasmussen Krogh , Loya Anand Chainsukh , Rossing Caroline Maria , Kistorp Thomas , Buch Kaare Fugleholm , Soelling Christine , Poulsgaard Lars , Benndorf Goetz , Feldt-Rasmussen Ulla

Head and neck paragangliomas (HNPGLs) are a type of neuroendocrine tumour. They arise from the sympathetic ganglia and can be either sporadic or due to hereditary syndromes (up to 40%). Most HNPGLs do not produce significant amounts of catecholamines1. Often, HNPGLs are detected in late stages due to compression or infiltration of cranial structures1. We report a case of a paraganglioma of the basis cranii due to somatic variants of SDHB (succinate dehydr...